Category Immunotherapy and Cancer Diagnostics Executive Statement Innovative antibodies targeting the immune checkpoint molecule CTHRC1 offer new therapeutic and diagnostic options for colorectal cancer. Description This technology involves the development of isolated antibodies and antigen-binding fragments specifically designed to target CTHRC1, a molecule playing a critical role in colorectal cancer [...]

Category Biomedical Therapeutics – Cancer Research Executive Statement Targeting and inhibiting FABPs offers a novel therapeutic strategy to reduce tumor growth and improve cancer patient outcomes. Description This technology involves methods to inhibit fatty acid binding proteins (FABPs), key players in the tumor microenvironment, using antibodies, nucleic acids, or small [...]

PROBLEM Many skin conditions include small areas which are difficult to treat with conventional topicals. SOLUTION Small adhesive patches with topical medications for spot treatments. VALUE/BENEFIT Improved treatment and patient satisfaction.

PROBLEM Beige adipocytes are a compelling interventional target for obesityrelated disorders given their propensity to stimulate weight loss and promote resistance to obesity through homeostatic control of energy balance. Naturally occurring beige adipocyte precursors isolated from human adipose tissue have limited expansion potential, and precursors from obese patients show a [...]